Advice on moving to St. Louis ?

I am really interseted in moving to a new city! My boyfriend and I have grown up in the philadelphia suburbs all our life and are looking to try something new. For some reason I have been really drawn to St. Louis! I will be graduating as a nurse in May and need advice on good ares to move to. We love the city and night life, but are big on safety. We are both 25 and grew up in traditional italian families. We are not so picky about price or the house itself. We just want to live in a great neighborhood for not only great activities but eventually raising a family! Any help would be great! thankyou! NIKKI